The saddest moment as Prime Minister is writing letters to families who have lost loved ones in Afghanistan or those who we have tried to help in hostage situations but it hasn't worked out.
In a global race, can we really justify the huge number of expensive peripheral European institutions? Can we justify a commission that gets ever larger? Can we carry on with an organisation that has a multibillion pound budget but not enough focus on controlling spending and shutting down programmes that haven't worked?
We cannot go on as we are with 2.6 million people on incapacity benefit, 500,000 of them are under 35. Are we really saying there are half a million people in this country under 35 who are simply too ill to work? I don't think that's right.
Cap the well, yes. Clear up the mess, yes. Make compensation - yes, absolutely. But would it be right to have legislation that independently targets BP rather than other companies? I don't think that - would be right.
From Caesar's legions to the Napoleonic wars. From the Reformation, the Enlightenment and the industrial revolution to the defeat of nazism. We have helped to write European history, and Europe has helped write ours.
I do think 'Gogglebox' is extraordinarily insightful, and I think if politicians want to understand how we are viewed at home, it's quite recommended viewing.
I mean, I'm a conservative. I believe that, you know, if you borrow too much, you just build up debts for your children to pay off. You put pressure on interest rates. You put at risk your economy. That's the case in Britain. We're not a reserve currency, so we need to get on and deal with this issue.
As far as I am concerned this referendum should settle the matter. I believe it will one way or another be decisive. Britain will not want to go through this again. On the other hand if we vote to leave, this really is irreversible.
For me, there is no greater sunshine in politics or in life than to have a job, security for your family, a good school place where you know your child is going, and the sense that if I put in, there will be a decent, secure retirement at the end of it all.
2012 has been an extraordinary year for our country. We cheered our Queen to the rafters with the Jubilee, showed the world what we're made of by staging the most spectacular Olympic and Paralympic Games ever and - let's not forget - punched way above our weight in the medals table.
There's another way we are getting behind business - by sorting out the banks. Taxpayers bailed you out. Now it's time for you to repay the favour and start lending to Britain's small businesses.
I think it true that, you know, sometimes things start to change even before a government changes and, actually, I think you can begin to see even the Labour machine beginning to understand that it has become over-reliant on targets and processes, that local governments have been over-bossed and bullied.
It does not seem to me that the steps which would be needed to make Britain - and others - more comfortable in their relationship in the European Union are inherently so outlandish or unreasonable.
Taken as a whole, Europe's share of world output is projected to fall by almost a third in the next two decades. This is the competitiveness challenge - and much of our weakness in meeting it is self-inflicted. Complex rules restricting our labour markets are not some naturally occurring phenomenon.
If we are going to try to get across to the poorest people in the world that we care about their plight and we want them to join one world with the rest of us, we have got to make promises and keep promises.
I went to a very posh school, I had a very privileged upbringing with parents who were incredibly loving and brilliant. I've never tried to hide that; I'm not going to change my accent or talk in a different way.
You will feel the full force of the law and if you are old enough to commit these crimes you are old enough to face the punishments. And to these people I would say this: you are not only wrecking the lives of others, you are potentially wrecking your own life too.
I believe very strongly that staying in is the right answer for Britain. And I haven't pulled my punches, I've fought this campaign the only way I know how, which is to lead from the front, to be clear about what I believe, to be clear about what the consequences are.
Half a century ago, the amazing courage of Rosa Parks, the visionary leadership of Martin Luther King, and the inspirational actions of the civil rights movement led politicians to write equality into the law and make real the promise of America for all her citizens.
I've said I'll stand for a full second term, but I think after that it will be time for new leadership. Terms are like Shredded Wheat - two are wonderful but three might just be too many.